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Histopathologic diagnosis of an atypical Spitz tumor will prompt consideration and discussion of sentinel node biopsy, with a clear discussion with the parents regarding the high positive rate of sentinel node studies among Spitz tumors and the challenges in interpreting these results

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LDs are generated by a gradual accumulation of neutral lipids in the hydrophobic core of the ER membrane, until a critical threshold is exceeded, causing a dilation of the hydrophobic core into a lens domain (Mahamid et al., 2019)