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PlexusDx's Precision Peptide Genetic Test identifies variants in peptide-processing pathways that influence how your body responds to GLP-1 therapy, including your individual risk for side effects like nausea
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TGR5 activity appears to not have been lost in type 2 diabetic humans whereby the infusion of CCK, or rectal taurocholate, causes GLP-1 and insulin release via the TGR5 axis in colonic L-cells and pancreatic -cells respectively (341, 342)
10.1016/j.bbrc.2019.06.112 46 ZhangY.CaoX.LiP.FanY.ZhangL.LiW.et al (2020)
Combining Ozempic with other diabetes medications can increase the risk of hypoglycemia