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Given its unique dual role as an anti-ferroptosis and pro-necroptosis agent, regulating the expression and subcellular localization of FSP1 in different pathological states represents a key step toward developing effective prognostic and treatment strategies for related diseases

'Damage is permanent' Pain in mice triggered the release of adrenaline and cortisol, making their hearts beat faster and blood pressure rise, affecting the nervous system and causing acute stress

The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder

For assessing GPX4 expression, we used samples derived from female C57BL/6J (Charles River Laboratories UK, RRID: IMSR_JAX:000664) mice transduced at 56 weeks of age

Glutathione can help to neutralise free radicals and toxins preventing their build up which can lead to cellular damage and oxidative stress

These important immunosuppressive changes were associated with increased synthesis of the immunoregulatory cytokine transforming growth factor- by colonic epithelial cells in Cl-2TG mice compared with WT littermates (Figure 2)