In the US, only topical diclofenac (solution and gel) has been FDA approved for use in osteoarthritis patients
[DOI] [PubMed] [Google Scholar] [114].Heidegger S, Gssl D, Schmidt A
Most manufacturers and regulatory guidelines recommend discarding opened vials after 28 days, regardless of how much solution remains
Injections were administered for five consecutive days to the respective experimental groups, starting on the eighth day of the study
That said, some hangover effects remain stubborn
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